
Mainolfi founded Kymera Therapeutics and raised over $1 billion to advance oral small molecule degraders — a class of medicines capable of hitting disease targets that conventional drugs cannot reach — pushing multiple first-in-class programs into clinical development.
Nello Mainolfi founded Kymera Therapeutics, a clinical-stage biotech advancing oral small-molecule degraders against disease targets inaccessible with conventional therapeutics.
Kymera has progressed multiple first-in-class programs into clinical trials, raised over $1 billion, and partnered with major biopharmaceutical companies. Before Kymera, Mainolfi was an entrepreneur in residence at Atlas Venture and led drug discovery teams at Novartis.

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