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Powered 500 Awards - 2026 

Awarded by the Editors of Powered Magazine to a select group of leaders whose work will define the decade ahead.

POWERED 500 AWARD PRESENTED TO

Alex Oshmyansky

Founder, Cost Plus Drug Company (Mark Cuban)

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POWERED MAGAZINE

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Alex Oshmyansky

Founder, Cost Plus Drug Company (Mark Cuban)

POWERED 500 WINNER 2026

Alex Oshmyansky is the Founder of Cost Plus Drugs, the online pharmacy (famously backed and co-branded with Mark Cuban) that has disrupted generic drug pricing in America. Oshmyansky, a practicing radiologist, founded the company after witnessing the absurd markups on generic medications that cost patients thousands of dollars more than necessary. Cost Plus Drugs operates on a transparent pricing model: cost + 15% margin + $3 pharmacy fee + $5 shipping. The company has exposed the enormous markups embedded in the traditional pharmaceutical supply chain, saving patients billions of dollars on generic medications. Cost Plus Drugs has grown rapidly since its 2022 launch, now offering over 2,000 medications and operating its own manufacturing facility in Dallas. The company has partnered with major health systems and employers and has even offered some cancer drugs at 80% discounts to traditional pricing. Oshmyansky's combination of medical expertise and entrepreneurial vision-addressing a problem he personally witnessed harming patients-exemplifies how domain expertise can drive meaningful consumer impact. His work has forced the entire pharmaceutical industry to reckon with pricing transparency.

Highlights from the 2026 list

Elon Musk
Neuralink
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Jeff Bezos
Amazon
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Satya Nadella
Microsoft
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Sundar Pichai
Alphabet Inc.
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 Sara Blakely
Spanx
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Sam Altman
Open AI
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Jensen Huang
Nvidia
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Whitney Wolfe Herd
Bumble
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Mark Zuckerberg
Meta
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Brian Chesky
Airbnb
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Oprah Winfrey
Harpo Productions / OWN Network
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Mark Cuban
Owner of Dallas Mavericks (Former)
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